Abstract
Background Chemotherapy uses anti-neoplastic agents, the drugs used to treat malignancies. Neutropenia is associated with cytotoxic therapy. Anti-neoplastic agents are poisonous to the cells, affecting the synthesis of folic acid and damaging the DNA, RNA, and protein that damage the bone marrow. Destruction of bone marrow decreases absolute neutrophil count in the blood. To assess the baseline data and practice of oncology nurses, develop and implement the evidence-based standard nursing protocol, assess the satisfaction level of the patients for the utility of the standard nursing protocol, find out the correlation between knowledge and practice and to associate the knowledge and practice score with selected demographic variables. Material And Method In the study quasi-experimental design was utilized. The study was conducted at Siddharth Gupta Memorial Cancer Hospital, Sawangi (Meghe), Wardha city, between June to Aug 2022 Result The result of the study shows the mean value per existing knowledge is 7.59 and practices is 37.95, post knowledge is 14.23, and post practices is 71.15. The standard deviation values of per exiting knowledge are 2.67 and, practice 3.09 and, post knowledge is 2.32, post practices are 1.32. The calculated t-value of knowledge is 46.57and the p-value is 0001. The calculated t-value of practice is 12.03, and the p-value is 0.0001. Conclusion The present research concluded that the knowledge and skills of oncology nurses are enhanced after implementing the standard nursing protocol.