Abstract
Significant strides have been made by researchers aiming to understand the crucial role of the plant cell wall (PCW) in defending against pathogens. Numerous reviews have synthesized findings on plant-pathogen interactions, shedding light on the role of the PCW in defence, the generation of cell wall damage-associated molecular patterns (DAMPs), perception, and signalling response. However, the role of the PCW in responses to herbivory remains underexplored. This review aims to fill this gap, offering a comprehensive analysis of the current knowledge in this area. For the first time, it consolidates studies focusing on the involvement of the PCW in pest response. The review examines key aspects, including the structural changes in the PCW following pest infestation, the role of cell wall-derived DAMPs, and the phenotypic traits of transgenic plants with modified cell wall components. Additionally, it delves into the genetic underpinnings of cell wall plasticity and the mechanisms of DAMP perception. Lastly, the article identifies promising research pathways to further unravel the complex role of the PCW in pest defence, encouraging advancements in this relatively nascent field. Through this effort, it aims to bridge the knowledge gap and inspire deeper investigations into the interplay between the PCW and pest resistance.