Differential expression of genes in elastase-induced saccular aneurysms with high and low aspect ratios

BACKGROUND: Morphologic features are thought to play a critical role in the rupture of intracranial, saccular aneurysms. OBJECTIVE: The objective of this study was to investigate the gene expression pattern of saccular aneurysms with distinct morphologic patterns. METHODS: Elastase-induced saccular aneurysms with high (>or= 2.4) and low (or= 1.5 and