Abstract
Rasmussen encephalitis is a chronic and progressive inflammatory encephalopathy, responsible for unilateral hemispheric damage causing focal epileptic seizures, hemiparesis and cognitive decline. It is an immune-mediated disease, with constant involvement of T lymphocytes. It generally progresses in three phases: a prodromal phase, an acute phase and a residual phase. The diagnostic criteria have been well established since the European consensus of 2005. Early injections of intravenous immunoglobulin and Natalizumab allowed a reduction in the frequency of seizures and cerebral inflammation. We report a case of Rasmussen encephalitis with a review of literature to shed light on this condition suffering from diagnostic delay or even diagnostic error.