Electrochemiluminescence Sensor Based on CeO(2) Nanocrystalline for Hg(2+) Detection in Environmental Samples

基于CeO(2)纳米晶的电化学发光传感器用于环境样品中Hg(2+)的检测

阅读:1

Abstract

The excessive concentration of heavy-metal mercury ions (Hg(2+)) in the environment seriously affects the ecological environment and even threatens human health. Therefore, it is necessary to develop rapid and low-cost determination methods to achieve trace detection of Hg(2+). In this paper, an Electrochemiluminescence (ECL) sensing platform using a functionalized rare-earth material (cerium oxide, CeO(2)) as the luminescent unit and an aptamer as a capture unit was designed and constructed. Using the specific asymmetric matching between Hg(2+) and thymine (T) base pairs in the deoxyribonucleic acid (DNA) single strand, the "T-Hg-T" structure was formed to change the ECL signal, leading to a direct and sensitive response to Hg(2+). The results show a good linear relationship between the concentration and the response signal within the range of 10 pM-100 µM for Hg(2+), with a detection limit as low as 0.35 pM. In addition, the ECL probe exhibits a stable ECL performance and excellent specificity for identifying target Hg(2+). It was then successfully used for spiked recovery tests of actual samples in the environment. The analytical method solves the problem of poor Hg(2+) recognition specificity, provides a new idea for the efficient and low-cost detection of heavy-metal pollutant Hg(2+) in the environment, and broadens the prospects for the development and application of rare-earth materials.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。