A mouse model of endometriosis mimicking the natural spread of invasive endometrium

模拟侵袭性子宫内膜自然扩散的子宫内膜异位症小鼠模型

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作者:Mike R Wilson, Jeanne Holladay, Ronald L Chandler

Methods

At 6 weeks of age, mice were subjected to salpingectomy surgery. Mice were followed until the time point of vaginal bleeding (average 17 weeks), or aged for 1 year in the case of control mice. At time of sacrifice, endometriotic lesions, ovaries and uterus were collected for the purpose of histochemical and immunohistochemical analyses. Samples were analyzed for markers of the endometriotic tissue and other relevant biomarkers. Main

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