Serum fetuin-A levels are associated with the presence and severity of coronary artery disease in patients with type 2 diabetes

血清胎球蛋白 A 水平与 2 型糖尿病患者的冠状动脉疾病的存在和严重程度相关

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作者:Zi-Wen Zhao, Chao-Gui Lin, Ling-Zhen Wu, Yu-Kun Luo, Lin Fan, Xian-Feng Dong, Hong Zheng

Conclusions

Fetuin-A might serve as a potential biomarker for reflecting the development and progression of CAD in T2DM patients.

Methods

A total of 241 consecutive patients with T2DM and 69 controls were recruited. Serum fetuin-A levels were analyzed by enzyme-linked immunosorbent assay. The presence and severity of CAD were evaluated by coronary angiography (CAG).

Objective

To clarify the correlation between serum fetuin-A levels and the presence and severity of coronary artery disease (CAD) in patients with type 2 diabetes (T2DM).

Results

Serum fetuin-A levels are independently correlated with the presence and severity of CAD in T2DM patients. Conclusions: Fetuin-A might serve as a potential biomarker for reflecting the development and progression of CAD in T2DM patients.

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