Bandage Contact Lens-Assisted Plaque Brachytherapy for Anterior Segment Tumors: A Novel Technique to Prevent Corneal Complications

绷带式隐形眼镜辅助斑块近距离放射治疗前段肿瘤:一种预防角膜并发症的新技术

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Abstract

Anterior segment tumors pose challenges in treatment due to their location and potential for globe loss. Plaque brachytherapy allows globe salvage, but placing plaques over the cornea and limbus may lead to epithelial defects and ulcers. We report a novel technique using a bandage contact lens as a buffer between the plaque and cornea in a 48-year-old woman with iridociliary melanoma. The lens thickness (0.07 mm) was included in radiation dose planning. The patient had no corneal complications and showed tumor regression at seven months. Two additional patients treated similarly showed stable tumors and no adverse effects at six months. This method may offer a safer alternative to amniotic membrane grafts for anterior segment brachytherapy, reducing corneal toxicity without compromising tumor control.

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