Abstract
Cancer continues to be a major factor in global mortality rates, presenting a substantial challenge to efforts aimed at extending life expectancies worldwide. Effective cancer treatment necessitates a multidisciplinary approach. India has a limited number of radiotherapy centres, and their distribution is uneven between urban and rural areas. Setting up a radiotherapy department is a complex process that demands thorough planning. The establishment of new radiotherapy departments involves a series of interconnected steps such as regulatory support, site selection, infrastructure design, civil works, recruitment of professional staff, equipment procurement, commissioning, and obtaining licenses. Mobilizing human resources, including training and forming a skilled team consisting of radiation oncologists, medical physicists, technologists, nursing officers, and support staff, is essential for proficient operation and patient care. Effective master planning for new radiotherapy facilities necessitates collaboration and involvement of highly specialized professionals from both the healthcare sector and the construction industry. Conducting a cost-benefit analysis is vital to ensure that the proposed facility meets the institute's objectives in terms of patient workload and clinical capability with sufficient institutional resources to support the program. The strategic placement of functional areas not only improves patient workflow and optimizes shielding needs but also enhances communication within the broader institution. In addition, designing a radiotherapy facility with vision and adaptable expansion capabilities ensures cost efficiency, allowing seamless evolution in response to future demands while maintaining uninterrupted services. Therefore, the article aims to discuss the challenges, and strategies for establishing a new radiation oncology department.