Insulin resistance and glucose and lipid concentrations in a cohort of perinatally HIV-infected Latin American children

一组围产期 HIV 感染的拉丁美洲儿童的胰岛素抵抗以及葡萄糖和脂质浓度

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作者:Rohan Hazra, Laura Freimanis Hance, Jacqueline Pontes Monteiro, Noris Pavia Ruz, Daisy Maria Machado, Mariza Saavedra, Fabrizio Motta, D Robert Harris; NISDI Pediatric Study Group 20

Abstract

We measured glucose, insulin and lipids in 249 perinatally HIV-infected Latin American children. Only 1 subject had impaired fasting glucose; 6.8% had insulin resistance. Abnormalities in total, low-density lipoprotein and high-density lipoprotein cholesterol and triglycerides were reported for 13%, 13%, 21% and 34%, respectively. Continued follow-up of this population is necessary to characterize the evolution and clinical consequences of these findings.

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