Large C9orf72 repeat expansions are not a common cause of Parkinson's disease

C9orf72 大片段重复扩增并非帕金森病的常见病因

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Abstract

The concept of a pathological overlap between neurodegenerative disorders is gaining momentum. We sought to determine the contribution of C9orf72 repeat expansions, recently discovered as a cause of frontotemporal dementia and amyotrophic lateral sclerosis, in a large number of Parkinson's disease patients. No large expansions were identified in our cohort.

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