Abstract
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: 1. To examine the effect of high‐dose chemotherapy regimens with autologous stem cell transplantation versus conventional chemotherapy on overall survival and progression‐free survival in patients with aggressive non‐Hodgkin lymphoma. 2. To identify factors that modify the effect of HD‐ASCT on overall survival and progression‐free survival in patients with aggressive non‐Hodgkin lymphoma.