Efficacy of Core Needle Biopsy in the Diagnosis of Pediatric Extracranial Solid Malignancies: A 10-Year Study

核心针穿刺活检在儿童颅外实体恶性肿瘤诊断中的疗效:一项为期10年的研究

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Abstract

INTRODUCTION: Core needle biopsies of solid masses in children are a minimally invasive technique. It guides to a definitive diagnosis and facilitates management. AIMS AND OBJECTIVES: To determine the accuracy, sensitivity, and specificity of core needle biopsies in diagnosing pediatric solid masses. MATERIALS AND METHODS: A retrospective analysis of 430 children, who underwent core needle biopsy for solid masses between January 2007 and December 2016 at CMC Vellore, was done. RESULTS: Retroperitoneal and intra-abdominal masses constituted 66% of cases. Real-time image guidance was used in 44% of cases. An accurate diagnosis was obtained in 93.6% of cases, while results did not correlate with the final diagnosis in 3.4%. Three percent had inadequate or necrotic tissue. None of the children had postprocedure complications. CONCLUSION: Core needle biopsies serve as good diagnostic modality, with minimal risks, in making a conclusive diagnosis and deciding on the line of management.

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