Abstract
OBJECTIVE: To investigate the correlation between metabolic syndrome (MS) indicators and locomotive syndrome (LS) in geriatric oncology inpatients. METHODS: This study enrolled 430 geriatric oncology inpatients at risk of LS, admitted to the Department of Oncology at Affiliated Hospital of Jiangnan University from January 2024 and December 2024. Waist circumference, diastolic blood pressure, systolic blood pressure, total cholesterol (TC), triacylglycerols (TG), fasting glucose, high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were measured as MS indicators. The Geriatric Locomotive Function Scale (GLFS-25) was used to assess LS. Subjects were classified into two groups: those with LS (322 cases) and those without (87 cases), to analyze the correlation between MS indicators and LS. RESULTS: 409 geriatric oncology inpatients completed the study. One-way linear regression analysis revealed that waist circumference, systolic blood pressure, diastolic blood pressure, TG, and LDL-C were positively correlated with GLFS-25 (p < 0.05), while HDL-C was negatively correlated in geriatric oncology inpatients (p < 0.05). Logistic regression analysis identified waist, systolic blood pressure, TG, and LDL-C as risk factors for developing LS in geriatric oncology inpatients (p < 0.05). CONCLUSION: Certain risk factors for MS are associated with increased GLFS-25 scores and the development of LS in geriatric oncology inpatients. Screening for LS is beneficial for the early diagnosis of MS and using LS as a focal point for intervention offers new insights into the comprehensive rehabilitation of geriatric oncology patients.