Does ozone gel enhance the bone width and buccal plate of bone thickness surrounding the implant following osseodensification? A randomized controlled clinical trial

臭氧凝胶能否在骨致密化后增加种植体周围骨的宽度和颊侧骨板的厚度?一项随机对照临床试验

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Abstract

PURPOSE: The present study was conducted to evaluate the effect of using ozone gel with transcrestal sinus elevation using osteotomes, on the bone width and the buccal plate of bone thickness around the implants placed simultaneously. MATERIALS AND METHODS: A total of 30 sinuses with an average residual alveolar bone height ranging from 4-7 mm participated in this randomized controlled clinical trial. Following a closed sinus lift procedure, patients were randomized into two groups: one for the ozone gel recipient group and the other for control group. Cone beam computed tomography was carried out both immediately and four months postoperatively. Radiographic evaluations were performed to assess bone width and labial plate thickness at both crestal and midcrestal levels. RESULTS: Radiographic analysis revealed that the mean bone width of the control group after four months postoperative was (8.54 ± 1.46 mm) compared to (8.96 ± 1.66 mm) in the study group, which was statistically insignificant (P ≤ .0.05). The mean labial plate of bone thickness value of the control group after four months postoperative was (1.86 ± 0.63 mm) compared to (1.89 ± 0.51 mm) in the study group. Although the bone dimensions in the study group was higher than the control group, it was statistically insignificant (P ≤ .0.05). CONCLUSION: When compared to the graftless group, the ozone gel recipient group showed non-significant difference in the results in terms of bone width and thickness. Both methods, nevertheless, produced outcomes that were acceptable. TRIAL REGISTRATION: This study protocol was retrospectively registered on the trial registry "Clinical trials.gov PRS". CLINICALTRIALS: gov ID is: NCT06604819 and the registration date is 20/9/2024.

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