Abstract
INTRODUCTION AND IMPORTANCE: Cutaneous lesions such as Marjolin's ulcer-a malignant transformation of chronic ulcerative wounds or scars into squamous cell carcinoma-and fungating soft tissue sarcomas, which are rapidly progressing tumours originating from mesenchymal tissues, exhibit a diverse range of clinical and pathological characteristics. These aggressive malignancies are characterized by high recurrence rates and poor prognoses. Traditionally, amputation was the primary treatment; however, limb salvage has become the preferred approach, necessitating extensive reconstruction with flap reconstruction. CASE PRESENTATION: In this report, we present two cases of Marjolin's ulcer and one case of a fungating soft tissue sarcoma, detailing their clinical presentations, diagnostic workups, and management. Each patient underwent wide tumour excision followed by abdominal flap reconstruction. CLINICAL DISCUSSION: The shift from amputation to limb-sparing surgery highlights the advancements in oncologic and reconstructive techniques, allowing for better functional and aesthetic outcomes. CONCLUSION: This report underscores the critical role of early detection and a multidisciplinary approach in optimizing limb preservation and functional outcomes.