N-(2,5-Dimeth-oxy-phen-yl)-6-nitro-quinazolin-4-amine

N-(2,5-二甲氧基苯基)-6-硝基喹唑啉-4-胺

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作者:Syed Muhammad Saad, Imran Khan, Shahnaz Perveen, Khalid M Khan, Sammer Yousuf

Abstract

In the title mol-ecule, C16H14N4O4, the quinazoline ring is substanti-ally planar (r.m.s. deviation = 0.0129 Å) and forms a dihedral angle of 2.73 (8)° with the benzene ring. The conformation of the mol-ecule is stabilized by an intra-molecular C-H⋯N hydrogen bond. In the crystal, mol-ecules are linked into chains running parallel to the b axis by C-H⋯O hydrogen bonds. In addition, π-π stacking is observed between dimethoxy-substituted and nitro-substituted benzene rings, with centroid-centroid distances in the range 3.6438 (10)-3.7148 (10) Å.

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