Synthesis and Activity of Ionic Antioxidant-Functionalized PAMAMs and PPIs Dendrimers

离子型抗氧化剂功能化PAMAM和PPI树状聚合物的合成与活性

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Abstract

For this study, new dendrimers were prepared from poly(propylene imine) (PPI) and polyamidoamine (PAMAM) dendrimers using an efficient acid-base reaction with various phenolic acids. The syntheses were also optimized in both microwave and microfluidic reactors. These ionic and hydrophilic dendrimers were fully characterized and showed excellent antioxidant properties. Their cytotoxic properties have been also determined in the case of fibroblast dermal cells.

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