Levonorgestrel as a Potential Trigger of Acute Bilateral Central Serous Chorioretinopathy: Case Report

左炔诺孕酮作为急性双侧中心性浆液性脉络膜视网膜病变的潜在诱发因素:病例报告

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Abstract

This is a first ever report describing a case of acute bilateral central serous chorioretinopathy which developed shortly after the consumption of levonorgestrel as emergency contraception. A 27-year-old female patient visited the emergency department of the clinic due to diminished visual acuity in both eyes. She had taken a single pill of levonorgestrel (1.5 mg) as emergency contraception 2 days prior. Fundus examination showed macular edema. Optical coherence tomography (OCT) revealed serous bilateral detachment of the macular retina. Fluorescein angiography showed a "smokestack" leakage of contrast in the right eye and focal macular leakage in the left eye. Ten days after oral diuretic and topical nonsteroidal anti-inflammatory drugs were prescribed, follow-up examination revealed improvement of best corrected visual acuity and OCT showed complete regression of subretinal fluid. One month and 3 months after the initial visit, the patient's best corrected visual acuity returned to 20/20 and OCT showed no signs of subretinal fluid. This case highlights levonorgestrel as a potential trigger for this serious chorioretinal condition, thus expanding on the literature on possible risk factors and mechanisms of development for central serous chorioretinopathy.

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