Bilateral acute macular neuroretinopathy after Epstein-Barr virus encephalitis

EB病毒脑炎后双侧急性黄斑神经视网膜病变

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Abstract

PURPOSE: To report a case of a 11-year-old girl, who developed a bilateral acute macular neuroretinopathy (AMN) after Epstein-Barr virus (EBV) encephalitis. OBSERVATIONS: Clinical findings and multimodal imaging including fundus photography, near-infrared reflectance, spectral-domain, and enhanced-deep imaging optical coherence tomography (OCT) of a patient with bilateral acute macular neuroretinopathy after Epstein-Barr virus encephalitis. CONCLUSIONS AND IMPORTANCE: After conducting a literature review in August 2024 using PubMed and Google Scholar, using the keywords "acute macular neuroretinopathy", "AMN", "Epstein-Barr", "Epstein-Barr virus", "EBV", "encephalitis" "Epstein-Barr encephalitis" "EBV encephalitis" we did not find any previous reports of AMN associated with EBV encephalitis, such as in our case. Near infrared imaging and spectral-domain optical coherence tomography are key diagnostic tools for this condition, even when fundoscopic findings are subtle.

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