Antiviral and anti-inflammatory effects of rosmarinic acid in an experimental murine model of Japanese encephalitis

迷迭香酸在日本脑炎小鼠实验模型中的抗病毒和抗炎作用

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Abstract

Rosmarinic acid (RA) reduced the mortality of mice infected with Japanese encephalitis virus (JEV). Significant decreases in viral loads (P < 0.001) and proinflammatory cytokine levels (P < 0.001) were observed in JEV-infected animals treated with RA compared to levels in infected mice without treatment, at 8 to 9 days postinfection.

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