Pulmonary miliary papillary/micropapillary adenocarcinoma manifesting as carcinomatous encephalitis

肺粟粒状乳头状/微乳头状腺癌表现为癌性脑炎

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Abstract

The histological pattern and the associated molecular aberrations have an important bearing in the prognosis of pulmonary adenocarcinomas. Papillary and micropapillary growth patterns with mutations in epidermal growth factor receptor and anaplastic large-cell lymphoma kinase rearrangements have an aggressive clinical course. We report one such cancer in a 49-year-old woman, where it assumed a miliary pattern in the lungs, and the patient presented with neurological symptoms related to carcinomatous encephalitis, an infrequent metastatic manifestation.

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