Hemoadsorption as Adjunctive Therapy in Streptococcal Toxic Shock Syndrome

血液吸附作为链球菌中毒性休克综合征的辅助治疗

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Abstract

Group A Streptococcus (GAS) is a Gram-positive bacterium that can lead to invasive infections, such as necrotizing fasciitis or streptococcal toxic shock syndrome (STSS), a condition associated with high morbidity and mortality rates. We report the case of a 70-year-old male admitted to the intensive care unit with septic shock and multiorgan failure due to GAS bacteremia. The patient was treated with broad-spectrum antibiotics, intravenous immunoglobulin, and organ support measures, including vasopressors, renal replacement therapy, and hemoadsorption using the Jafron HA380 cartridge. This approach led to progressive clinical improvement and a full recovery. Hemoadsorption may have contributed to the resolution of shock by reducing circulating inflammatory mediators. This case supports its potential as an adjunctive treatment in STSS.

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