Non-Invasive EEG Recordings in Epileptic Dogs (Canis familiaris)

对患有癫痫的犬(Canis familiaris)进行非侵入性脑电图记录

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Abstract

In addition to characteristic and easily identifiable behavioural signs-namely epileptic seizures-electroencephalography (EEG) has long been a standard component of epilepsy diagnosis protocols. In veterinary practice, EEG is typically performed in a semi-invasive manner, using subcutaneous electrodes and sedation. Here, we propose that the non-invasive polysomnography protocol, originally developed for basic research, can serve as a more welfare-friendly yet informative alternative for assessing epileptic brain activity in dogs. In this study, N = 11 family dogs diagnosed with epilepsy underwent a single non-invasive polysomnography session. EEG-based evidence for epileptic activity was detected in two cases. Polysomnography data from these 11 epileptic dogs were further analysed to evaluate sleep structure parameters. Compared to a matched control group of N = 11 clinically healthy dogs, the epileptic group exhibited reduced sleep efficiency, increased sleep latency, more wakings after sleep onset, and less time spent in drowsiness and non-REM sleep. These findings support the potential utility of non-invasive brain monitoring techniques, such as polysomnography, in the diagnosis and management of epilepsy in veterinary medicine.

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