Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus

早期产后聚合酶链式反应检测在识别丙型肝炎病毒围产期传播中的应用

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作者：Prasad,Mona,Sandoval,Grecio J,Saade,George R,Hughes,Brenna L,Clifton,Rebecca G,Reddy,Uma M,Bartholomew,Anna,Salazar,Ashley,Chien,Edward K,Tita,Alan T N,Thorp,John M,Metz,Torri D,Wapner,Ronald J,Sabharwal,Vishakha,Simhan,Hyagriv N,Swamy,Geeta K,Heyborne,Kent D,Sibai,Baha M,Grobman,William A,El-Sayed,Yasser Y,Casey,Brian M,Parry,Samuel,Macones,George A
期刊：Clinical Infectious Diseases影响因子：7.300
时间：2026起止号：2026 Feb 4;81(6):1102-1105
doi：10.1093/cid/ciaf266

Abstract

In this study, a single hepatitis C virus (HCV) RNA at 2-6 months was sensitive and specific (86.7% and 95% confidence interval [CI], 62.1%-96.3% and 100% and 95% CI, 98.8%-100%, respectively) in identifying perinatal transmission of HCV. No cases of perinatal infection requiring treatment were missed.

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