Abstract
OBJECTIVES: Magnesium plays a crucial role in metabolic homeostasis and energy balance. This study aims to evaluate the effect of magnesium in regulating nutritional status and inflammatory responses in nutritional support. METHODS: A survey of 86 lung cancer patients was conducted. The oral nutrition supplement group was given an oral nutritional solution that was magnesium-rich on the basis of the routine diet in the hospital, while a routine hospital diet was given to the control group. Changes in magnesium concentration, nutritional status, and inflammatory indicators were compared between groups. RESULTS: There was no significant difference in the indicators on 1st day and 10th day compared to the control group (P > .05). However, the levels of Mg, ALB, PA, Hb, and TLC in the oral nutrition supplement group were significantly increased, and the levels of TNF-α, IL-6, and CRP were significantly reduced on the 21st day (P < .05). CONCLUSIONS: Changes in magnesium concentration can improve nutritional status and inflammatory response. The synergistic effect of magnesium concentration and nutritional support may open a new avenue for the prevention and treatment of cancer patients.