Abstract
Syntheses and X-ray crystal structures of four 4-(4-meth-oxy-phen-yl)piperazin-1-ium (MeOPP) salts, with 2,2,2-tri-fluoro-acetate, C11H17N2O+·C2F3O2 - (I), 2,3,4,5,6-penta-fluoro-benzoate, C11H17N2O+·C7F5O2 -·H2O (II), 4-iodo-benzoate C11H17N2O+·C7H4IO2 -·H2O (III), and 4-methyl-benzoate, C11H17N2O+·C8H7O2 -·H2O (IV) anions are presented. The salts form directly from equimolar qu-anti-ties of N-(4-meth-oxy-phen-yl)piperazine and the corresponding organic acid in methanol and crystallize from 1:1 methanol/ethyl acetate. Salt I is anhydrous whereas II, III, and IV are all monohydrates. In all cases, the MeOPP cation conformation is determined by the torsion about the N-C bond between the piperazinium and 4-meth-oxy-benzene rings. Crystal packing in each structure is largely dictated by N-H⋯O and (in II, III, and IV) O-H⋯O hydrogen bonds, although each also features weak C-H⋯O-type hydrogen bonds. Salt II also has π-π-stacking inter-actions between cation and anion arene rings, and III exhibits I⋯I close contacts.