Abstract
Artificial ion channels with controllable mono/monovalent cation separation fulfill important roles in biomedicine, ion separation, and energy conversion. However, it remains a daunting challenge to develop an artificial ion channel similar to biological ion channels due to ion-ion competitive transport and lack of ion-gating ability of channels. Here, we report a conductive MXene membrane with polydopamine-confined angstrom-scale channels and propose a voltage gating and ion charge comediation strategy to concurrently achieve gated and selective mono/monovalent cation separation. The membrane shows a highly switchable "on-off" ratio of ∼9.9 for K(+) transport and an excellent K(+)/Li(+) selectivity of 40.9, outperforming the ion selectivity of reported membranes with electrical gating (typically 1.5 to 6). Theoretical simulations reveal that the introduced high-charge cations such as Mg(2+) enable the preferential distribution of target K(+) over competing Li(+) at the channel entrance, and the surface potential reduces the ionic transport energy barrier for allowing K(+) to pass quickly through the channel.