Augmentation of cytotoxic drug action and X-irradiation by antibodies

抗体增强细胞毒性药物作用和X射线照射

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Abstract

The effect of an antiserum containing antibodies against cell surface components of PyBHK cells on the action of certain anticancer agents has been studied using a colony formation inhibition assay. The effects of x-rays, chlorambucil, CCNU and possibly ICRF 159 are augmented by the antiserum whereas methotrexate and vinblastine are not.

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