To stop or not? Tamoxifen therapy for secondary prevention of breast cancer in a patient with ocular toxicity

停药还是继续?他莫昔芬治疗对出现眼部毒性的患者进行乳腺癌二级预防

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Abstract

We report a case of a patient with treated breast cancer whose dilated fundus examination showed crystalline deposits in the central region of the macula. She was taking tamoxifen for secondary prevention. Optical coherence tomography revealed individual refractile deposits associated with intraretinal cysts in both eyes. Tamoxifen-related retinopathy was suspected. A decision to discontinue treatment with tamoxifen was considered but had to be taken in conjunction with the oncologist.

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