Chabner Colloquium: Answering the Big Questions in Cancer Research & 2016 STO Annual Meeting (Boston, MA: November 11-12, 2016)

This brief communication describes the case of a patient with colorectal cancer with a TP53 germline mutation initially considered somatic because no TP53 germline mutation was noted in the liquid biopsy (cell‐free DNA) next‐generation sequencing assay.