BAT: Bisulfite Analysis Toolkit: BAT is a toolkit to analyze DNA methylation sequencing data accurately and reproducibly. It covers standard processing and analysis steps from raw read mapping up to annotation data integration and calculation of correlating DMRs

BAT:亚硫酸氢盐分析工具包:BAT 是一款用于准确、可重复地分析 DNA 甲基化测序数据的工具包。它涵盖了从原始序列比对到注释数据整合以及相关 DMR 计算的标准处理和分析步骤。

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Abstract

Here, we present BAT, a modular bisulfite analysis toolkit, that facilitates the analysis of bisulfite sequencing data. It covers the essential analysis steps of read alignment, quality control, extraction of methylation information, and calling of differentially methylated regions, as well as biologically relevant downstream analyses, such as data integration with gene expression, histone modification data, or transcription factor binding site annotation.

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