One-Year Daily Micronutrient Supplementation and Anemia Prevalence Among Mildly Stunted Infants in Bhaktapur, Nepal

尼泊尔巴克塔普尔轻度发育迟缓婴儿一年每日微量营养素补充与贫血患病率

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Abstract

OBJECTIVES: To describe the burden of anemia at 6 to 11 months and the change in anemia prevalence after 1 year of multi-micronutrient supplementation. METHODS: We analyzed hemoglobin concentration twice in 569 children. First when they were 6 to 11 months old and second after 1 year (at ages 18-23 months). All children were given a lipid-based micronutrient formulation daily for a year. RESULTS: The prevalence (95% CI) of anemia at 6 to 11 months was 65% (61%-68%) and decreased to 25% (21%-28%) after 1 year. Among the 367 infants with anemia at baseline, 29% continued to be anemic during follow-up. There were also 18% infants who developed anemia during follow-up out of 202 infants with normal hemoglobin concentration at baseline. CONCLUSIONS: The anemia prevalence was substantially reduced after 1 year with micronutrient supplementation. However, even after 1 year of multimicronutrient supplementation, one-fourth of toddlers had anemia which merits further integrated research and comprehensive intervention.

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