Abstract
To integrate and discuss the cutting-edge science and revolutionized therapeutics of cancer in Japan and the United States, JCA (Japanese Cancer Association)-AACR (American Association for Cancer Research) Joint Symposia were held on 25th (Symposium 2) and 26th (Symposium 1) in September 2014 as a part of the 73rd Annual Meeting of the Japanese Cancer Association at Pacifico Yokohama in Yokohama, Japan. The symposia focused on mouse genetics and human genomics in cancer research. Eight prominent scientists from JCA and AACR discussed their own research in the symposia. They provided substantial fruitful information not only for identification of novel target molecules and pathways in cancer therapeutics but also for direct translation of cancer genomics into clinics.