Abstract
Radiometals, with their favorable decay properties and rich coordination chemistry, have found widespread applications in both diagnostic and therapeutic nuclear medicine. To ensure effective utilization, radiometal-based radiopharmaceuticals are designed to target specific organs or cells. Radiometals are primarily produced in cyclotrons or reactors using stable isotopes as raw materials. Many countries, including Korea, are pursuing self-sufficiency in radiometal production at the government level. This review examines the current production and supply status of raw materials for key radiometals that are either actively used or expected to see a significant demand growth in the future in Korea. GRAPHICAL ABSTRACT: Flow of radiometal production.