Abstract
Effective segmentation of cervical cancer tissue from magnetic resonance (MR) images is crucial for automatic detection, staging, and treatment planning of cervical cancer. This study develops an innovative deep learning model to enhance the automatic segmentation of cervical cancer lesions. We obtained 4063 T2WI small-field sagittal, coronal, and oblique axial images from 222 patients with pathologically confirmed cervical cancer. Using this dataset, we employed a convolutional neural network (CNN) along with TransUnet models for segmentation training and evaluation of cervical cancer tissues. In this approach, CNNs are leveraged to extract local information from MR images, whereas Transformers capture long-range dependencies related to shape and structural information, which are critical for precise segmentation. Furthermore, we developed three distinct segmentation models based on coronal, axial, and sagittal T2WI within a small field of view using multidirectional MRI techniques. The dice similarity coefficient (DSC) and mean Hausdorff distance (AHD) were used to assess the performance of the models in terms of segmentation accuracy. The average DSC and AHD values obtained using the TransUnet model were 0.7628 and 0.8687, respectively, surpassing those obtained using the U-Net model by margins of 0.0033 and 0.3479, respectively. The proposed TransUnet segmentation model significantly enhances the accuracy of cervical cancer tissue delineation compared to alternative models, demonstrating superior performance in overall segmentation efficacy. This methodology can improve clinical diagnostic efficiency as an automated image analysis tool tailored for cervical cancer diagnosis.