Poor sleep and the metabolic derangements associated with obesity in adult males

成年男性肥胖相关的睡眠质量差和代谢紊乱

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Abstract

CONTEXT: Short sleep and obesity have a causal association with each other. Obesity is also associated with metabolic imbalances. However, a subset of 20%-30% of obese population have only few metabolic complications, known as metabolically healthy obese (MHO) and rest with worsened metabolic profile are known as metabolically abnormal obese (MAO). AIMS: To find the association between sleep quality and metabolic health of adult obese males. SETTINGS AND DESIGN: The study was a cross-sectional study conducted at medicine out-patient department of the institute. METHODS AND MATERIAL: In this study, hundred adult obese males of age group 25-60 years, with Body mass index (BMI) ≥ 25 Kg/m(2), were divided into MHO and MAO, based on their metabolic health using Joint Interim criteria. Sleep quality was assessed using Pittsburgh sleep questionnaire index (PSQI). STATISTICAL ANALYSIS USED: The data obtained were analyzed using PAST statistical software. RESULTS: The two groups MHO and MAO presented with significant differences in their mean age and BMI (P = 0.0001). The global score of PSQI was significantly high for MAO than MHO with mean values of 8.24 ± 3.60 and 6.65 ± 3.58, respectively (P = 0.016). Sleep disturbances score was significantly high in MAO (P = 0.0001). Significant associations were observed for global score with age, BMI, waist circumference, fasting blood sugar, and triglycerides. CONCLUSIONS: Poor sleep quality was significantly associated with detrimental metabolic profile and BMI. The metabolic health worsened with increasing age and obesity.

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