Investigation of Artery Wall Elasticity Effect on the Prediction of Atherosclerosis by Hemodynamic Factors

通过血流动力学因素研究动脉壁弹性对动脉粥样硬化预测的影响

阅读:1

Abstract

Atherosclerosis is a vascular disease in which some parts of the artery undergo stenosis due to the aggregation of fat. The causes and location of stenosis can be determined using fluid mechanics and parameters such as pressure, effective wall shear stress, and oscillatory shear index (OSI). The present study, for the first time, numerically investigates the pulsatile blood flow inside arteries with elastic and rigid walls in simple and double stenosis (80% stenosis) by using k-ω model and physiological pulse. The reason for applying the k-ω model in the present study was to provide more consistent results with clinical results to improve the accuracy in estimating atherosclerosis disease. The investigation of the time-mean wall shear stress indicated that for double stenosis, the difference between the results of the rigid and elastic artery assumptions is greater than the case of simple stenosis, so that this difference percent can be up to 2.5 times. In addition, the results showed that the pressure drop for the first stenosis is greater than the second stenosis, by 810 Pa (for solid artery) and 540 Pa (for elastic artery). The results also revealed that for simple stenosis, the length of the diseases prone zone in the elastic artery is 21% longer than the rigid one which this figure for double stenosis is calculated to be about 40%. Comparing the results of the simple stenosis with double, one affirmed that the artery wall thickness growth for case of double stenosis is greater than that of the single one.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。