High NUSAP1 expression predicts poor prognosis in colon cancer

NUSAP1 高表达预示结肠癌预后不良

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作者:Zhaoxiu Liu, Chengqi Guan, Cuihua Lu, Yanmei Liu, Runzhou Ni, Mingbing Xiao, Zhaolian Bian

Aim

Nucleolar and spindle-associated protein 1 (NUSAP1) is an indispensable mitotic regulator. Aberrant NUSAP1 expression is associated with perturbed mitosis and tumorigenesis. In this study, we investigated the clinical significance of NUSAP1 expression in colon cancer.

Conclusion

NUSAP1 is overexpressed in colon cancer and high expression of NUSAP1 acts as an independent predictive factor for poor prognosis in colon cancer.

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