Advanced topology of triply periodic minimal surface structure for osteogenic improvement within orthopedic metallic screw

三重周期最小表面结构的先进拓扑结构,用于骨科金属螺钉内的成骨改善

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作者:Wangwang Luo, Yang Wang, Zhonghan Wang, Jianhang Jiao, Tong Yu, Weibo Jiang, Mufeng Li, Han Zhang, Xuqiang Gong, Bo Chao, Shixian Liu, Xuhui Wu, Jincheng Wang, Minfei Wu

Abstract

Metallic screws are one of the most common implants in orthopedics. However, the solid design of the screw has often resulted in stress shielding and postoperative loosening, substantially impacting its long-term fixation effect after surgery. Four additive manufacturing porous structures (Fischer-Koch S, Octet, Diamond, and Double Gyroid) are now introduced into the screw to fix those issues. Upon applying the four porous structures, elastic modulus in the screw decreased about 2∼15 times to reduce the occurrence of stress shielding, and bone regeneration effect on the screw surface increased about 1∼50 times to improve bone tissue regrowing. With more bone tissue regrowing on the inner surface of porous screw, a stiffer integration between screw and bone tissue will be achieved, which improves the long-term fixation of the screw tremendously. The biofunctions of the four topologies on osteogenesis have been fully explored, which provides an advanced topology optimization scheme for the screw utilized in orthopedic fixation.

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