Low Serum Hepcidin Is Associated With Reduced Short-Term Survival in Adults With Acute Liver Failure

血清铁调素水平低与急性肝衰竭成人患者短期生存率降低有关

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作者:Igor Spivak, Jyoti Arora, Caitlyn Meinzer, Valerie Durkalski-Mauldin, William M Lee, Christian Trautwein, Robert J Fontana, Pavel Strnad; Acute Liver Failure Study Group (ALFSG)

Conclusion

Our findings demonstrate that several serum iron parameters significantly associate with 3-week outcomes in adults with ALF. Among them, hepcidin decreases early during experimental APAP-induced ALF, is an independent predictor and might be a useful component of future prognostic scores.

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