Abstract
BACKGROUND: Non-healthcare undergraduate students frequently seek drug-related information online, often relying on unverified sources such as Google or YouTube. Early exposure to professional drug information databases may promote evidence-based information-seeking habits. CASE PRESENTATION: A one-hour training session on using Lexicomp, a professional drug information database, was conducted for 55 non-healthcare students and 58 pharmacy students at a women's university in South Korea. The session included live demonstrations and guided search tasks. Participants completed pre- and post-training surveys assessing their information-seeking behaviors, perceptions of source reliability, and intention to use Lexicomp. Students also ranked drug information types they typically searched for and anticipated using Lexicomp to find. Only 1.8% of non-healthcare students had prior knowledge of Lexicomp, compared to 100% of pharmacy students. After the training, 100% of non-healthcare students rated Lexicomp as more reliable than their usual sources, and over 90% expressed willingness to use it in the future. A marked shift in information-seeking priorities was observed, with greater emphasis on clinically relevant topics such as adverse effects and contraindications. Students reported increased confidence and found the platform easier to use than expected. CONCLUSION: A brief educational intervention was effective in improving drug information literacy among non-healthcare students. Early training in professional resources may foster long-term adoption of evidence-based practices in personal health information use.