Abstract
BACKGROUND: This study evaluates the performance of the MC-80 automatic blood cell morphology analyzer in identifying the morphology of blood cells in patients with hematological diseases and normal samples. METHODS: A total of 320 patients with hematological diseases and 200 healthy persons with health examination from the health examination center between January 2023 and May 2024 were selected as research subjects, and 520 venous blood samples were collected in this study. The morphology of white blood cells, nucleated red blood cells, platelets, and mature red blood cells was all detected by the MC-80 automatic blood cell morphology analyzer and compared with the manual microscopic examination. The ability of the MC-80 automatic blood cell morphology analyzer in identifying the morphology of blood cells in patients with hematological diseases and normal samples was evaluated. RESULTS: MC-80 demonstrated high precision, sensitivity, specificity, negative predictive value, and positive predictive value indiscriminating different forms of blood cells. There was no significant difference in the accuracy of platelet clumps and segmented neutrophils preclassified by MC-80 compared with manual verification. The accuracy of all the cells was >90% after verification. Turnaround time showed no significant difference in total turnaround time between MC-80 analysis and manual counting. CONCLUSION: The MC-80 automatic blood cell morphology analyzer is a reliable and powerful blood cell morphology analyzer in analyzing the morphology of most blood cells in patients with hematological diseases and normal samples.