A Case of Hypervascular Vestibular Schwannoma with Ventricular Enlargement Improved by the Tumor Volume Reduction Effect of Preoperative Embolization

一例伴有脑室扩大的高血管性前庭神经鞘瘤,经术前栓塞缩小肿瘤体积后病情得到改善

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Abstract

OBJECTIVE: Reports on embolization of the feeding arteries for vestibular schwannomas are limited, and studies addressing the tumor volume reduction effect of embolization are similarly scarce. Here, we present a case of a patient with vestibular schwannoma and associated ventricular enlargement, in which preoperative embolization led to substantial tumor volume reduction and subsequent improvement in ventricular enlargement. CASE PRESENTATION: The patient was a 32-year-old man presenting with hearing loss, headache, nausea, unsteadiness, and loss of appetite. MRI displayed a left vestibular schwannoma with a maximum diameter of 38 mm and associated ventricular enlargement. Angiography displayed a hypervascular vestibular schwannoma with feeders from the left anterior inferior cerebellar artery (AICA) and the petrosal branch of the middle meningeal artery (MMA). Embolization was performed using 25% N-butyl cyanoacrylate for the AICA and 500-700-μm Embosphere microspheres diluted 60 times for the MMA. Symptomatic improvement was observed 2 days after the procedure. MRI conducted 4 days after the procedure showed a 19.8% reduction in tumor volume and mild ventricular shrinkage. The patient underwent tumor resection 7 days post-embolization and had a favorable postoperative course. CONCLUSION: Although the tumor volume reduction effect of preoperative embolization does not always lead to an improvement in ventricular enlargement, our present case demonstrates that preoperative embolization can contribute to the improvement of ventricular enlargement through its volume reduction effect.

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