Coping with copper: a bibliometric analysis of copper's role in cancer pathogenesis and treatment

应对铜:铜在癌症发病机制和治疗中的作用的文献计量分析

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Abstract

This bibliometric analysis on copper's role in cancer pathogenesis and treatment, spanning from 2014 to 2024, provides a comprehensive overview of current trends and emerging research areas. It highlights China's dominance in research output and identifies a seminal 2022 study by Tsvetkov Peter as the most cited, cementing its importance in the field. Central keywords such as "DNA damage," "trace elements," and "oxidative stress" reflect the critical roles copper plays in cancer biology. As the field continues to evolve, key areas of focus for future studies are expected to include copper homeostasis, the roles of cuproptosis and ferroptosis, and the development of cancer prognosis models based on cuproptosis. This analysis offers valuable insights for advancing both scientific inquiry and clinical applications in this area.

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