Abstract
CONTEXT: Prostate cancer is the leading cancer diagnosis in males. The most common metastatic site of metastases in patients with prostate cancer is the axial skeleton and local lymph nodes. Rarely has there been a description of metastatic prostate cancer to the stomach, esophagus, small bowel, and rectum. CASE REPORT: We report an unusual case of a patient who was diagnosed with prostate cancer with synchronous metastasis to both the stomach and sigmoid colon. A 71-year-old African American man with a history of prostate cancer was admitted with a hemoglobin level of 6.1 g/dl, which had decreased from the baseline value of 8 g/dl. He underwent an esophagogastroduodenoscopy, which revealed a nodule in the fundus of stomach; a biopsy of the nodule was done. The patient also underwent a sigmoid polypectomy. Both surgical specimens were histopathologically consistent with metastatic adenocarcinoma of prostatic origin. CONCLUSION: To the best of our knowledge, this is the first case report in literature of synchronous metastasis of prostate cancer to both the stomach and sigmoid colon.