Finite element modeling of finite deformable, biphasic biological tissues with transversely isotropic statistically distributed fibers: toward a practical solution

具有横向各向同性统计分布纤维的有限可变形双相生物组织的有限元建模:迈向实用解决方案

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Abstract

The distribution of collagen fibers across articular cartilage layers is statistical in nature. Based on the concepts proposed in previous models, we developed a methodology to include the statistically distributed fibers across the cartilage thickness in the commercial FE software COMSOL which avoids extensive routine programming. The model includes many properties that are observed in real cartilage: finite hyperelastic deformation, depth-dependent collagen fiber concentration, depth- and deformation-dependent permeability, and statistically distributed collagen fiber orientation distribution across the cartilage thickness. Numerical tests were performed using confined and unconfined compressions. The model predictions on the depth-dependent strain distributions across the cartilage layer are consistent with the experimental data in the literature.

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