Pilot Study to Assess the Ability of a 4-Week, Home-Based, Electrical Muscle Stimulation Program to Improve Lower Extremity Function and Reduce Sarcopenia in Older Individuals With Cancer

一项试点研究旨在评估为期 4 周的居家电刺激肌肉疗法能否改善老年癌症患者下肢功能并减轻肌肉减少症

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Abstract

OBJECTIVE: To assess the effectiveness of home-based self-rehabilitation using a portable electrical muscle stimulation (EMS) device for improving severe sarcopenia by improving lower extremity function. DESIGN: The effect of 4 weeks of EMS training on improving lower extremity function was compared between patients divided into 2 groups based on baseline lower extremity function. Self-rehabilitation was carried out with a portable EMS device, the SIXPAD Foot Fit, and each session lasted 15-23 minutes. Lower extremity function was assessed with the Short Physical Performance Battery (SPPB). SETTING: University hospital. PARTICIPANTS: The study included 50 older outpatients (N=50) with a mean age of 75 years; 98% had hepatobiliary cancer, and 38% were men. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Patients were divided into 2 groups based on baseline SPPB value (SPPB ≤ 9 or SPPB >9). Lower extremity function was observed prospectively during 4 weeks of home-based self-rehabilitation. RESULTS: EMS was used consistently, with a median duration of use of 28 days. In the baseline SPPB>9 group, lower extremity function was not significantly improved (SPPB, 11.0-12.0; P=.290). In contrast, significant improvement was observed in the baseline SPPB ≤ 9 group, and the total score (SPPB score, 8.0-9.0; P=.001) and 2 of its 3 components, balance (balance score, 3.0-4.0; P=.009) and gait speed (gait speed score, 3.0-4.0; P=.002), improved significantly. Sit-to-stand ability did not improve (Sit-to-stand score, 1.0-2.0; P=.060). As a result, the proportion of patients with severe sarcopenia was initially 66.7% but decreased significantly to 36.4% (P=.002). CONCLUSIONS: A home-based, self-rehabilitation program using a portable EMS device may improve lower extremity function and attenuate sarcopenic status in older patients with cancer with reduced lower extremity function.

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