Abstract
Extravascular lung water (EVLW) is a basic symptom of congestive heart failure and other conditions. Computed tomography (CT) is standard to assess EVLW, but it requires ionizing radiation and radiology facilities. Lung ultrasound reverberation artifacts called B-lines have been used to assess EVLW. However, B-line artifact analysis relies on visual interpretation and subjects to inter-observer variability. We developed lung ultrasound surface wave elastography (LUSWE) to measure lung surface wave speed. This research aims to develop LUSWE to measure the change of lung surface wave speed due to lung water in an ex vivo swine lung model. The surface wave speeds of a fresh ex vivo swine lung were measured at four frequencies of 100 Hz, 200 Hz, 300 Hz, and 400 Hz. An amount of water was then filled into the lung through its trachea. Ultrasound imaging was used to guide the water filling until significant changes were visible on the imaging. The lung surface wave speeds were measured. An additional 120 ml of water was then filled into the lung. The lung surface wave speeds were then measured again. The results demonstrated that the lung surface wave speed decreased with respect to water content.