PROOF OF CONCEPT FOR A DEVICE TO STANDARDIZE CELLULAR MIGRATION ASSAY EXPERIMENTS

用于标准化细胞迁移分析实验的装置的概念验证

阅读:5

Abstract

One of the most common techniques for investigating the migration of human cells in culture is a "scratch assay" where a pipette tip is dragged through a layer of cells creating a "wound". Migration is then observed as the cells move back into the area that was cleared. While common, this method has drawbacks. It requires a seasoned hand to perform the "scratch", it leaves behind wounded remains of cells creating a unique microenvironment, and by design, the scratch is jagged and ununiform in nature. This research demonstrates the functionality of a cheap, easy to implement 3D printed device that mimics this assay. Its benefits include needing virtually no training to use, creating uniform areas for migration, and limiting cell death.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。